From a 'GTO' standpoint you probably need to call some reasonable % here, but against the way most people play then folding is probably your best option.

Facing this sizing, you will def have to call wider then A2+ with taking this line to avoid exploitation. And given our play pof, I think we keep his range sufficiently wide to allow us to bluffcatch here. Plus, we unblock all clubs and backdoors on flop that may start betting. Given, flop check, this hand is wp.

I agree with Fluxrazza, think you are beat by far most of the time on the river. Don't really think he barrels 3 like this with worse than AJ most of the time. But yes, would def call here with A4s etc...
Though obviously if you always took this line it is exploitable.