Hey guys, havent been active here lately cause I've been at the series.  This hand came up and I'd like your thoughts.

Playing 2/5 at MGM...Capped buy in at 1k.  I have 3100 in front and I am directly to the left of villain who has 1100ish.  Villains image is very loose, he has been raising blind, and has been caught semi bluffing once big.  He semi bluff shoved the turn heads up when (he turned a diamond draw and gut shot, the opponent called him with top pair but a diamond fell on river)

The loose reg is a good player but seems to have no discipline or money management skills (self proclaimed).

My image is not as loose as his, but I have been the second most active, and most active before he arrived, I didn't get out of line at any point and had shown done nothing too goofy.  The loose reg knows I am a winning player.

I have A4 spades.  We see a flop of Ah Js Qs.  We are 4 handed and I am MP.  I believe villain is first to act. (sorry, details a little fuzzy, the two people behind me were short stack fishies tho)  He leads for 45. into a pot of 60-80ish.  Call or raise, and if raise, how much?