What to do with middle pocket pairs (66s-10s) when getting 4bet??

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What to do with middle pocket pairs (66s-10s) when getting 4bet??

If I 3bet someone with a middle pocket pair and they decide to 4bet me. What should I be thinking about when making my next decision? Should I be calling with these hands or do I fold?? and what factors should I be using to decide when to call or fold??

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