Hand 1:

Villain is a tighter reg who plays mostly PLO. I don't have many hands with him.

$5000 effective
6 handed

UTG (hero) raises to $50 with 5s4s
4 folds
BB calls $50

Flop ($110) Ac Ks 2c
BB checks
Hero bets $50
BB calls

Turn ($210) 2s
BB checks
Hero bets ???

I think everyone will agree that this spot is a bet, but what size do you like and why?

Hand 2:

Villain is LAGgy to a fault. He opens too much, bluffs too much, and occasionally value bets hands that should not be value bet if his opponent takes a passive line. He also folds to 3bets a lot, which is reasonable given how loose he opens. He's a solid winner because he is capable of exploiting fish well and a lot of other regs in the game play very tight/straightforward.

He views me as a very good player. I have shown up with weak hands like T6s, 87o occasionally after 3betting him on BTN.

$5600 effective
7 handed

3 folds
CO raises to $75
BTN (hero) raises to $250 with KcKh
2 folds
CO calls

Flop ($535) Tc8d4c
CO checks
Hero bets $325
CO raises to $900
Hero calls

Turn 9s ($2335)
CO bets $1600 ($2850 behind)
Hero ?

He can have all sets and T8s and is likely to fast play all of them. He would never take this line with worse for value and I can't really nail down his bluffing range despite having a lot of hours with him. I suspect on the flop he can have a lot of club draws, J9s, 76s, maybe some backdoor diamonds, maybe 65s and QJs.