I was trying out a MP vs BB scenario, and I was unsure, so I used GTO+ to see what it does. The spot is following. The details of the GTO+ sim are given at the bottom of this post. (I think I used too wide of a BB defence range.)

MP opens to 3BB, BB defends. Flop is A93r. MP c-bets 33% pot.

What I discovered is that even if MP c-bets 100% of their range, BB folds half of their hands! This goes completely against the MDF principle, but I see lots of spots like this where the solvers don't follow MDF.

What's happening here (I think) is that MP's range is extremely strong on this flop: MP has a 62-38 equity advantage. So BB has to massively overfold on the flop.

[Details of sim:
MP opening range (from Grinder's Manual): AA-66,AKs-A2s,KQs-KTs,QJs-QTs,JTs,T9s,98s,AKo-ATo,KQo-KJo
BB defend range (from PokerSnowie preflop advisor): 99-22,ATs-A6s,A4s-A2s,KJs-K7s,QTs-Q9s,JTs-J9s,T9s-T8s,98s-97s,87s-86s,76s-75s,65s-64s,54s,AQo-ATo,KQo-KJo,QJo,[50.0]TT,AJs,A5s,KQs,QJs[/50.0]

I disallowed donk-betting and node-locked MP to c-bet 33% with 100% of range.
]