Do you 2barrel sometimes with good blocker hand against active looking opponent?
Update: I have checked it in Solver. Solver doesn´t take this combo at all because it blocks Backdoor Flushdraws. He takes AdQh and AhQx. Other Combos are better like QJs (better blockers), 87s, 88, A3 (hands with outs). And AJ with one heart at least.

Hand History for Game 1111111111 (Poker Stars)
$5.00 USD NL Texas Hold'em - Tuesday, May 07, 01:52:55 ET 2019
Table Donati (Real Money)
Seat 1 is the button
Seat 1: Hero ( $7.13 USD ) - VPIP: 21, PFR: 16, 3B: 6, AF: 2,0, Hands: 52635
Seat 2: Player2 ( $7.49 USD ) - VPIP: 23, PFR: 14, 3B: 18, AF: 0,0, Hands: 22
Seat 3: Player3 ( $2.50 USD ) - VPIP: 43, PFR: 43, 3B: 0, AF: 2,5, Hands: 21
Seat 4: Player4 ( $13.81 USD ) - VPIP: 16, PFR: 12, 3B: 9, AF: 0,0, Hands: 69
Seat 5: Player5 ( $7.59 USD ) - VPIP: 24, PFR: 24, 3B: 8, AF: 0,0, Hands: 29
Seat 6: Player6 ( $5.18 USD ) - VPIP: 28, PFR: 28, 3B: 20, AF: 0,5, Hands: 18
Player2 posts small blind [$0.02 USD].
Player3 posts big blind [$0.05 USD].
* Dealing down cards *
Dealt to Hero [ As Qc ]
Player4 folds
Player5 folds
Player6 raises [$0.12 USD]
Hero raises [$0.40 USD]
Player2 folds
Player3 folds
Player6 calls [$0.28 USD]
* Dealing Flop * [ 4h, 6s, Kc ]
Player6 checks
Hero bets [$0.37 USD]
Player6 calls [$0.37 USD]
* Dealing Turn * [ 5h ]
Player6 checks
Hero bets [$1.08 USD]
Player6 calls [$1.08 USD]
* Dealing River * [ 5d ]
Player6 checks
Hero checks
Player6 shows [Ks, Js ]
Player6 wins $3.61 USD from main pot
Hero doesn't show [As, Qc ]