First sorry for my english :) I am asking a general and theorical question.

We take a given expected winrate (this winrate depend of your skills and opponent's skills). So this expected winrate will be different function the lineup we are playing . The question is : in which lineup we can expect the higher winrate ?

Scheme example: 

a) 1 big fish + 4 good regs (1 big negative winrate + 4 positive winrates superior or egal to yours)   

b) 2 slight fishs + 3 good regs (2 negative winrates + 3 positive ....)       

c) 1 slight fish + 4 bad regs (1 negative + 3 positive but inferior winrates than yours)

Obviously depend of many factors as position .... But my question is more about the impact of opponent's winrate on ours. 

Any thoughts ?